Migraine and headaches

Lien entre les hormones sexuelles et la migraine

Link between sex hormones and migraine

New research published in November 2022 highlights the key role of sex hormones in migraine , especially in women. These results enrich the data of...
Le dysfonctionnement mitochondrial impliqué dans les migraines

Mitochondrial dysfunction implicated in migraines

In the 1930s, it was suggested that migraine was associated with a decrease in blood sugar (Gray et al. 1935). Despite this hypothesis of the...
Dépression corticale envahissante : origine de l'aura migraineuse

Invasive cortical depression: origin of migraine aura

Pervasive cortical depression: the origin of migraine aura? Pervasive cortical depression is probably the cause of the migraine aura. The more research advances, the more...
Les voies descendantes de la douleur

The descending paths of pain

Part 3 - Neuro-vascular hypothesis The descending paths of pain The descending pain pathways (figure 3) make it possible to modulate the nociceptive response, either...
Altération du complexe sensitif du trijumeau et des voies ascendantes

Alteration of the trigeminal sensory complex and ascending pathways

Part 2 - Neurovascular hypothesis: Alteration of the trigeminal sensory complex and ascending pathways A. Sensitization of the trigeminal sensory complex When sensitization of the...
L'hypothèse neuro-vasculaire pour expliquer les céphalées

The neurovascular hypothesis to explain headaches

1. Periphery: neurogenic inflammation, sensitization of nociceptors For a long time, several theories described migraine as a vascular disorder with headache attributed solely to the...
Le PACAP & VIP des neuropeptides de l'inflammation

The PACAP & VIP of inflammatory neuropeptides

The adenylate cyclase activating polypeptide (PACAP) is a neuropeptide involved in migraine discovered in 1989, thanks to its ability to stimulate the formation of cAMP...
Les voies ascendantes de la douleur

The ascending paths of pain

Nociceptive information from the meninges and their vessels is relayed via ascending pathways , from the trigeminal sensory complex to the brainstem and diencephalon (Figure...
Anatomie du système trigémino-vasculaire

Anatomy of the trigeminovascular system

The trigemino-vascular system, its role in migraine In a few simple words: The trigeminovascular system is an essential component in the pathophysiology of migraine ....
Dysfonctionnement de l'hypothalamus

Dysfunction of the hypothalamus

Hypothalamus involved in migraine The hypothalamus located in the central nervous system plays an essential role in the release of endocrine hormones. It is a...